Fair Value Measurements - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value, Recurring - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Cash Equivalents
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	$ 129,825	$ 227,016
Gross Unrealized Holding Gains	7
Gross Unrealized Holding Losses	(2)
Estimated Fair Value	129,830	227,016
Cash Equivalents | Money Market Funds | Level 1
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	74,981	224,671
Estimated Fair Value	74,981	224,671
Cash Equivalents | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	54,644
Gross Unrealized Holding Gains	7
Gross Unrealized Holding Losses	(2)
Estimated Fair Value	54,649
Cash Equivalents | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	200	2,345
Estimated Fair Value	200	2,345
Short-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	327,940	298,295
Gross Unrealized Holding Gains	5	1
Gross Unrealized Holding Losses	(5,538)	(329)
Estimated Fair Value	322,407	297,967
Short-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	278,844	162,854
Gross Unrealized Holding Gains	5	1
Gross Unrealized Holding Losses	(4,859)	(195)
Estimated Fair Value	273,990	162,660
Short-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	49,096	135,441
Gross Unrealized Holding Losses	(679)	(134)
Estimated Fair Value	48,417	135,307
Long-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	26,709	196,919
Gross Unrealized Holding Losses	(886)	(1,038)
Estimated Fair Value	25,823	195,881
Long-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	26,709	176,492
Gross Unrealized Holding Losses	(886)	(925)
Estimated Fair Value	25,823	175,567
Long-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost		20,427
Gross Unrealized Holding Losses		(113)
Estimated Fair Value		20,314
Financial Assets
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	484,844	722,656
Gross Unrealized Holding Gains	12	1
Gross Unrealized Holding Losses	(6,426)	(1,367)
Estimated Fair Value	478,430	721,290
Other Assets | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	370	426
Estimated Fair Value	370	426
Short-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	59,429	56,382
Estimated Fair Value	59,429	56,382
Short-term Financial Liabilities | Cobalt Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	59,429	51,382
Estimated Fair Value	59,429	51,382
Short-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost		5,000
Estimated Fair Value		5,000
Long-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	117,411	199,886
Estimated Fair Value	117,411	199,886
Long-term Financial Liabilities | Cobalt Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	81,701	102,361
Estimated Fair Value	81,701	102,361
Long-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	35,710	97,525
Estimated Fair Value	35,710	97,525
Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	176,840	256,268
Estimated Fair Value	$ 176,840	$ 256,268