Acquisitions - Additional Information (Details) - USD ($)	1 Months Ended	3 Months Ended		9 Months Ended		44 Months Ended
	Feb. 28, 2019	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Dec. 31, 2021
Business Acquisition [Line Items]
Goodwill		$ 140,627,000		$ 140,627,000		$ 140,627,000	$ 140,627,000
Estimated fair value of contingent consideration, short term liabilities		59,429,000		59,429,000		59,429,000	51,382,000
Estimated fair value of contingent consideration, long-term liabilities		81,701,000		81,701,000		81,701,000	102,361,000
Contingent consideration				(12,613,000)	$ 10,080,000	89,900,000
Acquisition Agreement | Cobalt Biomedicine Inc
Business Acquisition [Line Items]
Business acquisition, percentage of voting interests acquired	100.00%
Business combination, intangible assets	$ 59,200,000
Goodwill	140,600,000
Business acquisition, impairment of intangible assets or goodwill	0
Maximum contingent consideration upon achievement of certain pre-specified development milestones	$ 500,000,000.0
Maximum period expected to achieve for success payments	20 years
Acquisition Agreement | Cobalt Biomedicine Inc | Research and Development Expense
Business Acquisition [Line Items]
Estimated fair value of contingent consideration		141,100,000		141,100,000		141,100,000	153,700,000
Estimated fair value of contingent consideration, short term liabilities		59,400,000		59,400,000		59,400,000	51,400,000
Estimated fair value of contingent consideration, long-term liabilities		81,700,000		81,700,000		81,700,000	102,300,000
Change in estimated fair value of success payment		(2,400,000)	$ (21,800,000)	56,500,000	(46,900,000)
Contingent consideration		8,300,000	$ 8,500,000	12,600,000	$ (10,100,000)
Acquisition Agreement | Cobalt Biomedicine Inc | Long-term Liabilities | Research and Development Expense
Business Acquisition [Line Items]
Estimated fair value of success payment liability		$ 31,900,000		$ 31,900,000		$ 31,900,000	$ 88,300,000
Acquisition Agreement | Cobalt Biomedicine Inc | Minimum
Business Acquisition [Line Items]
Threshold market capitalization	$ 8,100,000,000
Acquisition Agreement | Cobalt Biomedicine Inc | Market Capitalization Equal to or Exceeds $8.1 billion
Business Acquisition [Line Items]
Cobalt success payment	$ 500,000,000.0