Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	IPO	Convertible Preferred Stock	Common Stock	Common Stock IPO	Additional Paid-in Capital	Additional Paid-in Capital IPO	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ (421,184)			$ 2		$ 8,216		$ 30	$ (429,432)
Beginning balance (in shares) at Dec. 31, 2020			134,113
Beginning balance at Dec. 31, 2020			$ 852,897
Beginning balance (in shares) at Dec. 31, 2020				16,170
Conversion of convertible preferred stock into common stock upon initial public offering	852,897			$ 13		852,884
Conversion of convertible preferred stock into common stock, upon initial public offering (in shares)			(134,113)
Conversion of convertible preferred stock into common stock, upon initial public offering			$ (852,897)
Conversion of convertible preferred stock into common stock, upon initial public offering (in shares)				134,113
Issuance of common stock in initial public offering, net of offering costs		$ 626,405			$ 3		$ 626,402
Issuance of common stock in initial public offering, net of offering costs (in shares)					27,025
Vesting of restricted stock (in shares)				1,428
Exercise of stock options	298					298
Exercise of stock options (in shares)				205
Stock-based compensation expense	4,158					4,158
Unrealized loss on marketable securities, net	26							26
Net income (loss)	(180,617)								(180,617)
Ending balance at Mar. 31, 2021	881,983			$ 18		1,491,958		56	(610,049)
Ending balance (in shares) at Mar. 31, 2021				178,941
Beginning balance at Dec. 31, 2020	(421,184)			$ 2		8,216		30	(429,432)
Beginning balance (in shares) at Dec. 31, 2020			134,113
Beginning balance at Dec. 31, 2020			$ 852,897
Beginning balance (in shares) at Dec. 31, 2020				16,170
Net income (loss)	(161,934)
Ending balance at Jun. 30, 2021	905,897			$ 18		1,497,232		13	(591,366)
Ending balance (in shares) at Jun. 30, 2021				180,576
Beginning balance at Mar. 31, 2021	881,983			$ 18		1,491,958		56	(610,049)
Beginning balance (in shares) at Mar. 31, 2021				178,941
Vesting of restricted stock (in shares)				1,423
Exercise of stock options	333					333
Exercise of stock options (in shares)				212
Stock-based compensation expense	4,941					4,941
Unrealized loss on marketable securities, net	(43)							(43)
Net income (loss)	18,683								18,683
Ending balance at Jun. 30, 2021	905,897			$ 18		1,497,232		13	(591,366)
Ending balance (in shares) at Jun. 30, 2021				180,576
Beginning balance at Dec. 31, 2021	$ 728,502			$ 18		1,515,210		(1,366)	(785,360)
Beginning balance (in shares) at Dec. 31, 2021	184,929			184,929
Vesting of restricted stock				$ 1		(1)
Vesting of restricted stock (in shares)				1,419
Exercise of stock options	$ 652					652
Exercise of stock options (in shares)				284
Stock-based compensation expense	7,755					7,755
Unrealized loss on marketable securities, net	(3,806)							(3,806)
Net income (loss)	(31,448)								(31,448)
Ending balance at Mar. 31, 2022	701,655			$ 19		1,523,616		(5,172)	(816,808)
Ending balance (in shares) at Mar. 31, 2022				186,632
Beginning balance at Dec. 31, 2021	$ 728,502			$ 18		1,515,210		(1,366)	(785,360)
Beginning balance (in shares) at Dec. 31, 2021	184,929			184,929
Exercise of stock options (in shares)	604
Net income (loss)	$ (103,913)
Ending balance at Jun. 30, 2022	$ 639,505			$ 19		1,535,106		(6,347)	(889,273)
Ending balance (in shares) at Jun. 30, 2022	188,430			188,430
Beginning balance at Mar. 31, 2022	$ 701,655			$ 19		1,523,616		(5,172)	(816,808)
Beginning balance (in shares) at Mar. 31, 2022				186,632
Vesting of restricted stock (in shares)				1,243
Exercise of stock options	571					571
Exercise of stock options (in shares)				320
Issuance of common stock related to employee stock purchase plan	1,008					1,008
Issuance of common stock related to employee stock purchase plan, Shares				235
Stock-based compensation expense	9,911					9,911
Unrealized loss on marketable securities, net	(1,175)							(1,175)
Net income (loss)	(72,465)								(72,465)
Ending balance at Jun. 30, 2022	$ 639,505			$ 19		$ 1,535,106		$ (6,347)	$ (889,273)
Ending balance (in shares) at Jun. 30, 2022	188,430			188,430