Fair Value Measurements - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value, Recurring - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Cash Equivalents
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	$ 182,314	$ 227,016
Gross Unrealized Holding Losses	(7)
Estimated Fair Value	182,307	227,016
Cash Equivalents | Money Market Funds | Level 1
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	134,923	224,671
Estimated Fair Value	134,923	224,671
Cash Equivalents | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	46,941
Gross Unrealized Holding Losses	(7)
Estimated Fair Value	46,934
Cash Equivalents | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	450	2,345
Estimated Fair Value	450	2,345
Short-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	293,861	298,295
Gross Unrealized Holding Gains		1
Gross Unrealized Holding Losses	(3,718)	(329)
Estimated Fair Value	290,143	297,967
Short-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	240,016	162,854
Gross Unrealized Holding Gains		1
Gross Unrealized Holding Losses	(3,198)	(195)
Estimated Fair Value	236,818	162,660
Short-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	53,845	135,441
Gross Unrealized Holding Losses	(520)	(134)
Estimated Fair Value	53,325	135,307
Long-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	97,386	196,919
Gross Unrealized Holding Gains	4
Gross Unrealized Holding Losses	(2,626)	(1,038)
Estimated Fair Value	94,764	195,881
Long-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	87,007	176,492
Gross Unrealized Holding Gains	4
Gross Unrealized Holding Losses	(2,317)	(925)
Estimated Fair Value	84,694	175,567
Long-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	10,379	20,427
Gross Unrealized Holding Losses	(309)	(113)
Estimated Fair Value	10,070	20,314
Financial Assets
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	573,938	722,656
Gross Unrealized Holding Gains	4	1
Gross Unrealized Holding Losses	(6,351)	(1,367)
Estimated Fair Value	567,591	721,290
Other Assets | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	377	426
Estimated Fair Value	377	426
Short-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	51,386	56,382
Estimated Fair Value	51,386	56,382
Short-term Financial Liabilities | Cobalt Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	51,386	51,382
Estimated Fair Value	51,386	51,382
Short-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost		5,000
Estimated Fair Value		5,000
Long-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	131,516	199,886
Estimated Fair Value	131,516	199,886
Long-term Financial Liabilities | Cobalt Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	97,999	102,361
Estimated Fair Value	97,999	102,361
Long-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	33,517	97,525
Estimated Fair Value	33,517	97,525
Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	182,902	256,268
Estimated Fair Value	$ 182,902	$ 256,268