Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended	12 Months Ended
Mar. 31, 2022	Dec. 31, 2021
Stock Options
Stock Options Outstanding, Beginning Balance	17,337
Stock Options, Granted	8,045
Stock Options, Exercised	(284)
Stock Options, Forfeited/Cancelled	(270)
Stock Options Outstanding, Ending Balance	24,828	17,337
Stock Options Exercisable	5,139
Weighted-Average Exercise Price per Share
Weighted-Average Exercise Price per Share Outstanding, Beginning Balance	$ 8.96
Weighted-Average Exercise Price per Share, Granted	5.98
Weighted-Average Exercise Price per Share, Exercised	2.26
Weighted-Average Exercise Price per Share, Forfeited/Cancelled	13.98
Weighted-Average Exercise Price per Share Outstanding, Ending Balance	8.02	$ 8.96
Weighted-Average Exercise Price Per Share Exercisable	$ 5.35
Weighted-Average Remaining Contractual Life (years)
Weighted-Average Remaining Contractual Life (years), Outstanding	8 years 10 months 24 days	8 years 8 months 12 days
Weighted-Average Remaining Contractual Life (years), Exercisable	8 years 1 month 6 days
Aggregate Intrinsic Value
Aggregate Intrinsic Value, Outstanding	$ 62,772	$ 141,718
Aggregate Intrinsic Value, Exercisable	$ 20,355

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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Weighted average price of options that were either forfeited or expired.

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Gross number of share options (or share units) granted during the period.

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Number of options outstanding, including both vested and non-vested options.

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Amount by which current fair value of underlying stock exceeds exercise price of fully vested and expected to vest exercisable or convertible options. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Amount by which current fair value of underlying stock exceeds exercise price of fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted average price at which option holders acquired shares when converting their stock options into shares.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Weighted average remaining contractual term for vested portions of options outstanding and currently exercisable or convertible, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Number of share options (or share units) exercised during the current period.

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