Commitments and Contingencies - Additional Information (Details) - Extension	1 Months Ended	3 Months Ended
	Apr. 30, 2022	Mar. 31, 2022
Lessee Lease Description [Line Items]
Operating lease, renew period	5 years
Lessee, operating lease, option to extend	option to extend
Weighted-average remaining lease term		9 years 7 months 6 days
Weighted-average incremental borrowing rate		8.95%
Seattle Operating Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, renew period		5 years
Lessee, operating lease, existence of option to extend [true false]		true
Lessee, operating lease, option to extend		The Seattle and South San Francisco lease agreements each provide the Company with the option to renew for an additional period of five years
South San Francisco Operating Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, renew period		5 years
Lessee, operating lease, existence of option to extend [true false]		true
Lessee, operating lease, option to extend		The Seattle and South San Francisco lease agreements each provide the Company with the option to renew for an additional period of five years
Fremont, CA
Lessee Lease Description [Line Items]
Operating lease, renew period		5 years
Lessee, operating lease, existence of option to extend [true false]		true
Lessee, operating lease, option to extend		option to extend for up to two additional five-year terms
Lessee, operating lease, initial term		10 years
Fremont, CA | Maximum [Member]
Lessee Lease Description [Line Items]
Number of additional extensions permitted		2
Rochester,NY
Lessee Lease Description [Line Items]
Operating lease, renew period		2 years
Rochester,NY | Maximum [Member]
Lessee Lease Description [Line Items]
Number of additional extensions permitted		2