Fair Value Measurements - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value, Recurring - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Cash Equivalents
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	$ 137,949	$ 227,016
Gross Unrealized Holding Gains	2	0
Gross Unrealized Holding Losses	(1)	0
Estimated Fair Value	137,950	227,016
Cash Equivalents | Money Market Funds | Level 1
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	79,955	224,671
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	79,955	224,671
Cash Equivalents | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	57,744
Gross Unrealized Holding Gains	2
Gross Unrealized Holding Losses	(1)
Estimated Fair Value	57,745
Cash Equivalents | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	250	2,345
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	250	2,345
Short-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	325,842	298,295
Gross Unrealized Holding Gains	0	1
Gross Unrealized Holding Losses	(1,981)	(329)
Estimated Fair Value	323,861	297,967
Short-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	210,105	162,854
Gross Unrealized Holding Gains	0	1
Gross Unrealized Holding Losses	(1,540)	(195)
Estimated Fair Value	208,565	162,660
Short-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	115,737	135,441
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	(441)	(134)
Estimated Fair Value	115,296	135,307
Long-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	148,206	196,919
Gross Unrealized Holding Gains	4	0
Gross Unrealized Holding Losses	(3,196)	(1,038)
Estimated Fair Value	145,014	195,881
Long-term Marketable Securities | US Government Agencies Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	130,651	176,492
Gross Unrealized Holding Gains	4	0
Gross Unrealized Holding Losses	(2,820)	(925)
Estimated Fair Value	127,835	175,567
Long-term Marketable Securities | Corporate Debt Securities | Fair Value, Inputs, Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	17,555	20,427
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	(376)	(113)
Estimated Fair Value	17,179	20,314
Financial Assets
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	612,417	722,656
Gross Unrealized Holding Gains	6	1
Gross Unrealized Holding Losses	(5,178)	(1,367)
Estimated Fair Value	607,245	721,290
Other Assets | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	420	426
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	420	426
Short-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	50,900	56,382
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	50,900	56,382
Short-term Financial Liabilities | Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	50,900	51,382
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	50,900	51,382
Short-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost		5,000
Gross Unrealized Holding Gains		0
Gross Unrealized Holding Losses		0
Estimated Fair Value		5,000
Long-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	149,930	199,886
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	149,930	199,886
Long-term Financial Liabilities | Contingent Consideration | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	102,315	102,361
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	102,315	102,361
Long-term Financial Liabilities | Success Payment Liabilities | Fair Value, Inputs, Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	47,615	97,525
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	47,615	97,525
Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	200,830	256,268
Gross Unrealized Holding Gains	0	0
Gross Unrealized Holding Losses	0	0
Estimated Fair Value	$ 200,830	$ 256,268