Acquisitions - Additional Information (Details) - USD ($)	1 Months Ended	3 Months Ended		38 Months Ended
	Feb. 28, 2019	Mar. 31, 2022	Mar. 31, 2021	Mar. 31, 2022	Dec. 31, 2021
Business Acquisition [Line Items]
Goodwill		$ 140,627,000		$ 140,627,000	$ 140,627,000
Estimated fair value of contingent consideration, short term liabilities		50,900,000		50,900,000	51,382,000
Estimated fair value of contingent consideration, long-term liabilities		102,315,000		102,315,000	102,361,000
Contingent consideration		(528,000)	$ 11,393,000	102,000,000.0
Acquisition Agreement | Cobalt Biomedicine Inc
Business Acquisition [Line Items]
Business acquisition, percentage of voting interests acquired	100.00%
Business combination, intangible assets	$ 59,200,000
Goodwill	140,600,000
Business acquisition, impairment of intangible assets or goodwill	0
Maximum contingent consideration upon achievement of certain pre-specified development milestones	$ 500,000,000.0
Maximum period expected to achieve for success payments	20 years
Acquisition Agreement | Cobalt Biomedicine Inc | Research and Development Expense
Business Acquisition [Line Items]
Estimated fair value of success payment liability		41,500,000		41,500,000	88,300,000
Estimated fair value of contingent consideration		153,200,000		153,200,000	153,700,000
Estimated fair value of contingent consideration, short term liabilities		50,900,000		50,900,000	51,400,000
Estimated fair value of contingent consideration, long-term liabilities		102,300,000		$ 102,300,000	$ 102,300,000
Change in estimated fair value of success payment		(46,800,000)	91,800,000
Contingent consideration		$ 500,000	$ 11,400,000
Acquisition Agreement | Cobalt Biomedicine Inc | Minimum
Business Acquisition [Line Items]
Threshold market capitalization	$ 8,100,000,000
Acquisition Agreement | Cobalt Biomedicine Inc | Market Capitalization Equal to or Exceeds $8.1 billion
Business Acquisition [Line Items]
Cobalt success payment	$ 500,000,000.0