Basic and diluted net loss per common share is calculated by dividing net loss by the weighted-average number of common shares outstanding during the period, without consideration for common stock equivalents. The Company was in a loss position for all periods presented; therefore, basic net loss per share and diluted net loss per share are the same for all periods, as the inclusion of all potential common securities outstanding would have been anti-dilutive.

The following table summarizes the calculation of basic and diluted net loss per share of common stock:

	Three Months Ended March 31,
	2022			2021
	(in thousands, except per share amounts)
Net loss	$	(31,448	)	$	(180,617	)
Weighted-average number of common shares - basic and diluted		185,955			119,131
Net loss per common share - basic and diluted	$	(0.17	)	$	(1.52	)

The following securities were excluded from the computation of net loss per diluted share of common stock for periods presented as their effect would have been anti-dilutive:

	Three Months Ended March 31,
	2022		2021
	(in thousands)
Options to purchase common stock		24,828		15,781
Unvested restricted common stock		2,959		8,637
Unvested RSUs		810		325
Total		28,597		24,743