Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) shares in Thousands, $ in Thousands	Total	Series A-2 Convertible Preferred Stock	Series B Convertible Preferred Stock	Convertible Preferred Stock	IPO	Cumulative Effect, Period of Adoption, Adjustment	Common Stock	Common Stock IPO	Additional Paid-in Capital	Additional Paid-in Capital IPO	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit	Accumulated Deficit Cumulative Effect, Period of Adoption, Adjustment
Beginning balance at Dec. 31, 2018	$ (13,188)					$ (102)			$ 59			$ (13,247)	$ (102)
Beginning balance (in shares) at Dec. 31, 2018				11,463
Beginning balance at Dec. 31, 2018				$ 45,721
Beginning balance (in shares) at Dec. 31, 2018							1,577
Accounting Standards Update [Extensible Enumeration]	us-gaap:AccountingStandardsUpdate201602Member
Issuance of convertible preferred stock, net of issuance costs		$ 223,739
Issuance of convertible preferred stock, net of issuance costs, (in shares)		56,003
Issuance of convertible preferred stock for acquisition, non-cash		$ 135,971
Issuance of convertible preferred stock for acquisition, non-cash (in shares)		36,442
Issuance of convertible preferred stock in connection with license agreements		$ 11,928
Issuance of convertible preferred stock in connection with license agreements (in shares)		2,982
Vesting of restricted stock	$ 1						$ 1
Vesting of restricted stock (in shares)							8,425
Stock-based compensation	1,498								1,498
Exercise of stock options	1								1
Exercise of stock options (in shares)							1
Unrealized gain on marketable securities, net	26										$ 26
Net loss	(130,778)											(130,778)
Ending balance at Dec. 31, 2019	(142,542)						$ 1		1,558		26	(144,127)
Ending balance (in shares) at Dec. 31, 2019				106,890
Ending balance at Dec. 31, 2019				$ 417,359
Ending balance (in shares) at Dec. 31, 2019							10,003
Issuance of convertible preferred stock, net of issuance costs	435,538
Issuance of convertible preferred stock, net of issuance costs, (in shares)			27,223
Issuance of common stock in connection with license agreement	680								680
Issuance of common stock in connection with license agreement (in shares)							100
Vesting of restricted stock	1						$ 1
Stock-based compensation	5,829								5,829
Exercise of stock options	149								149
Exercise of stock options (in shares)							103
Unrealized gain on marketable securities, net	4										4
Net loss	(285,305)											(285,305)
Ending balance at Dec. 31, 2020	$ (421,184)						$ 2		8,216		30	(429,432)
Ending balance (in shares) at Dec. 31, 2020	134,113			134,113
Ending balance at Dec. 31, 2020	$ 852,897			$ 852,897
Ending balance (in shares) at Dec. 31, 2020	16,170						16,170
Vesting of restricted stock, (in Shares)							5,964
Conversion of convertible preferred stock into common stock upon initial public offering	$ 852,897						$ 13		852,884
Conversion of convertible preferred stock into common stock, upon initial public offering (in shares)	(134,113)
Conversion of convertible preferred stock into common stock, upon initial public offering	$ (852,897)
Conversion of convertible preferred stock into common stock, upon initial public offering (in shares)							134,113
Issuance of common stock in initial public offering, net of offering costs					$ 626,405			$ 3		$ 626,402
Issuance of common stock in initial public offering, net of offering costs (in shares)								27,025
Vesting of restricted stock (in shares)							5,916
Issuance of common stock related to employee stock purchase plan	2,179								2,179
Issuance of common stock related to employee stock purchase plan, Shares							119
Stock-based compensation	22,362								22,362
Exercise of stock options	$ 3,167								3,167
Exercise of stock options (in shares)	1,586						1,586
Unrealized gain on marketable securities, net	$ (1,396)										(1,396)
Net loss	(355,928)											(355,928)
Ending balance at Dec. 31, 2021	$ 728,502						$ 18		$ 1,515,210		$ (1,366)	$ (785,360)
Ending balance (in shares) at Dec. 31, 2021	0
Ending balance (in shares) at Dec. 31, 2021	184,929						184,929