Commitments and Contingencies - Additional Information (Details)	12 Months Ended
	Dec. 31, 2021 Extension
Lessee Lease Description [Line Items]
Lease arrangement, contractual expiration period, beginning year	2024-04
Lease arrangement, contractual expiration period, ending year	2031-11
Weighted-average remaining lease term	9 years 10 months 17 days
Weighted-average incremental borrowing rate	9.15%
Seattle Operating Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, renew period	5 years
Lessee, operating lease, existence of option to extend [true false]	true
Lessee, operating lease, option to extend	The Seattle and South San Francisco lease agreements each provide the Company with the option to renew for an additional period of five years.
South San Francisco Operating Lease Agreement
Lessee Lease Description [Line Items]
Operating lease, renew period	5 years
Lessee, operating lease, existence of option to extend [true false]	true
Lessee, operating lease, option to extend	The Seattle and South San Francisco lease agreements each provide the Company with the option to renew for an additional period of five years.
Fremont, CA
Lessee Lease Description [Line Items]
Operating lease, renew period	5 years
Lessee, operating lease, existence of option to extend [true false]	true
Lessee, operating lease, option to extend	option to extend for up to two additional five-year terms.
Lessee, operating lease, initial term	10 years
Fremont, CA | Maximum
Lessee Lease Description [Line Items]
Number of additional extensions permitted	2