Fair Value Measurements - Changes in Estimated Fair Value of Level 3 Financial Liabilities (Details) - Level 3 - USD ($) $ in Thousands	3 Months Ended
	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021
Contingent Consideration
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	$ 131,981	$ 140,457	$ 133,294	$ 121,901
Changes in fair value - expense (gain)	21,762	(8,476)	7,163	11,393
Ending Balance	153,743	131,981	140,457	133,294
Cobalt Success Payment Liability
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	111,609	89,819	156,451	64,694
Changes in fair value - expense (gain)	(23,256)	21,790	(66,632)	91,757
Ending Balance	88,353	111,609	89,819	156,451
Harvard Success Payment Liability
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	22,583	19,144	35,700	11,800
Changes in fair value - expense (gain)	(8,411)	3,439	(16,556)	23,900
Ending Balance	$ 14,172	$ 22,583	$ 19,144	$ 35,700