Fair Value Measurements - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value, Recurring - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Cash Equivalents
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	$ 227,016	$ 90,224
Gross Unrealized Holding Gains		1
Gross Unrealized Holding Losses		(1)
Estimated Fair Value	227,016	90,224
Cash Equivalents | Money Market Funds | Level 1
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	224,671	48,359
Estimated Fair Value	224,671	48,359
Cash Equivalents | Corporate Debt Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	2,345	1,138
Estimated Fair Value	2,345	1,138
Cash Equivalents | US Government and Agencies Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost		40,727
Gross Unrealized Holding Gains		1
Gross Unrealized Holding Losses		(1)
Estimated Fair Value		40,727
Short-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	298,295	253,435
Gross Unrealized Holding Gains	1	30
Gross Unrealized Holding Losses	(329)	(7)
Estimated Fair Value	297,967	253,458
Short-term Marketable Securities | Corporate Debt Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	135,441	8,798
Gross Unrealized Holding Losses	(134)	(2)
Estimated Fair Value	135,307	8,796
Short-term Marketable Securities | US Government and Agencies Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	162,854	244,637
Gross Unrealized Holding Gains	1	30
Gross Unrealized Holding Losses	(195)	(5)
Estimated Fair Value	162,660	244,662
Long-term Marketable Securities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	196,919	33,724
Gross Unrealized Holding Gains		7
Gross Unrealized Holding Losses	(1,038)
Estimated Fair Value	195,881	33,731
Long-term Marketable Securities | Corporate Debt Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	20,427
Gross Unrealized Holding Losses	(113)
Estimated Fair Value	20,314
Long-term Marketable Securities | US Government and Agencies Securities | Level 2
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	176,492	33,724
Gross Unrealized Holding Gains		7
Gross Unrealized Holding Losses	(925)
Estimated Fair Value	175,567	33,731
Other Assets | Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	426
Estimated Fair Value	426
Financial Assets
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	722,656	377,383
Gross Unrealized Holding Gains	1	38
Gross Unrealized Holding Losses	(1,367)	(8)
Estimated Fair Value	721,290	377,413
Short-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	56,382
Estimated Fair Value	56,382
Short-term Financial Liabilities | Contingent consideration | Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	51,382
Estimated Fair Value	51,382
Short-term Financial Liabilities | Success Payment Liabilities | Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	5,000
Estimated Fair Value	5,000
Long-term Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	199,886
Estimated Fair Value	199,886
Long-term Financial Liabilities | Contingent consideration | Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	102,361	121,901
Estimated Fair Value	102,361	121,901
Long-term Financial Liabilities | Success Payment Liabilities | Level 3
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	97,525	76,494
Estimated Fair Value	97,525	76,494
Financial Liabilities
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Amortized Cost	256,268	198,395
Estimated Fair Value	$ 256,268	$ 198,395