License and Collaboration Agreements - Additional Information (Details) - USD ($)	1 Months Ended		3 Months Ended		6 Months Ended
	Jun. 30, 2020	Mar. 31, 2019	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020	Dec. 31, 2020
Series B Convertible Preferred Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Share issue price							$ 16.00
Harvard College
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Share issue price		$ 4.00
Maximum period expected to achieve for success payments		12 years
Estimated fair value of success payment liability			$ 19,100,000		$ 19,100,000		$ 11,800,000
Harvard College | Series B Convertible Preferred Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License payment upon closing of equity financing	$ 6,000,000.0
Harvard College | Research and Development
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
(Gain) expense in connection with change in estimated fair value of success payment liability			(16,600,000)	$ 4,400,000	7,300,000	$ 4,600,000
Harvard College | Short-term Liabilities
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Estimated fair value of success payment liability			5,000,000.0		5,000,000.0		0
Harvard College | Long-term Liabilities
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Estimated fair value of success payment liability			$ 14,100,000		$ 14,100,000		$ 11,800,000
Harvard College | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential success payment		$ 175,000,000.0