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Income Taxes - Reconciliation of Income Taxes Computed Using U.S Federal Statutory Tax Rate (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract]      
Federal statutory tax $ (51,275)    
Valuation allowance 44,102    
Stock-based compensation 5,431    
Contingent consideration 3,097    
Success payment liabilities 2,864    
Other non-deductible items 908    
Research and development credits (5,222)    
Other 95    
Effective income tax rate $ 0    
Effective Income Tax Rate Continuing Operations Tax Rate Reconciliation [Abstract]      
Federal statutory tax 21.00% 21.00% 21.00%
State income tax, net of federal benefit   (6.31%) 15.38%
Valuation allowance (18.06%) (18.00%) (45.30%)
Stock-based compensation (2.22%)    
Success payment liabilities (1.17%) 0.55% 0.58%
Contingent consideration (1.27%) 0.05% 3.02%
Other non-deductible items (0.37%)    
Research and development credits 2.14%    
Tax credits   3.83% 6.59%
Other (0.04%) (1.12%) (1.27%)
Effective income tax rate 0.00% 0.00% 0.00%