Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2025

Share-Based Payment Arrangement [Abstract]

Schedule of Stock Based Compensation Expense Recognized

Stock-based compensation expense is recognized in the consolidated statements of operations as follows:

	Year Ended December 31,
	2025		2024		2023
	(in thousands)
Research and development	$	15,193	$	23,365	$	23,240
General and administrative		10,271		14,313		12,293
Total stock-based compensation expense	$	25,464	$	37,678	$	35,533

Schedule of Unrecognized Stock-Based Compensation Costs Related to Unvested Awards and Weighted-Average Period Over Which Costs are Expected to be Recognized

Unrecognized stock-based compensation costs related to unvested awards and the weighted-average period over which the costs are expected to be recognized as of December 31, 2025 are as follows:

	Stock Options		RSUs
Unrecognized stock-based compensation expense (in thousands)	$	22,421	$	14,206
Weighted-average period costs expected to be recognized (in years)		2.3		2.6

Summary of Stock Option Activity

A summary of the Company’s stock option activity is as follows:

	Stock Options (in thousands)			Weighted-Average Exercise Price per Share		Weighted-Average Remaining Contractual Life (in years)		Aggregate Intrinsic Value (in thousands)
Outstanding as of December 31, 2024		25,062		$	7.16		7.4	$	271
Granted		6,008			2.83
Exercised		(978	)		2.19
Forfeited/Cancelled		(7,150	)		7.61
Outstanding as of December 31, 2025		22,942		$	6.10		7.1	$	11,384
Exercisable as of December 31, 2025		14,190		$	7.07		6.1	$	3,861

Schedule of Assumptions Used in Black-Scholes Option-Pricing Model for Estimating Fair Value of Stock Options Granted

The fair value of stock options granted to employees, directors, and consultants was estimated on the date of grant using the Black-Scholes option pricing model using the following assumptions:

	Year Ended December 31,
Assumptions	2025	2024	2023
Risk free interest rate	3.7% – 4.4%	3.7% – 4.7%	3.36% – 4.98%
Expected volatility	75.0% – 77.5%	72.5% – 75.0%	70.0% – 72.5%
Expected term (years)	5.43 – 6.50	5.50 – 6.25	5.50 – 6.50
Expected dividend	0%	0%	0%

Summary of Additional Information Related to Stock Option Activity

The following table summarizes additional information related to stock option activity:

	Year Ended December 31,
	2025		2024		2023
Weighted average grant date fair value per share for options granted	$	1.96	$	5.82	$	2.62
Aggregate intrinsic value of stock options exercised (in thousands)	$	2,123	$	8,006	$	3,532

Summary of RSU Activity

A summary of the Company’s RSU activity is as follows:

	RSUs (in thousands)			RSUs Weighted-Average Grant Date Fair Value per Share
Unvested as of December 31, 2024		3,570		$	6.72
Granted		2,742			3.28
Vested		(1,515	)		5.45
Forfeited		(969	)		5.35
Unvested as of December 31, 2025		3,828		$	5.09