Organization - Additional Information (Details) - USD ($) shares in Thousands	1 Months Ended		3 Months Ended			9 Months Ended
	Aug. 31, 2025	Feb. 29, 2024	Sep. 30, 2025	Jun. 30, 2025	Mar. 31, 2024	Sep. 30, 2025	Sep. 30, 2024	May 08, 2025	Dec. 31, 2024
Description Of Organization [Line Items]
Accumulated deficit			$ 1,790,191,000			$ 1,790,191,000			$ 1,604,850,000
Cash, cash equivalents and marketable securities			153,100,000			153,100,000
Success payment liabilities			11,300,000			11,300,000
Contingent consideration			63,900,000			63,900,000
Net proceeds from issuance of common stock						$ 109,724,000	$ 181,000,000
At The Market Offering
Description Of Organization [Line Items]
Aggregate common stock value sold			$ 28,625,000	$ 315,000	$ 1,037,000
Over Allotment Option
Description Of Organization [Line Items]
Number of warrants to purchase common stock	1,500	12,700
Net proceeds from issuance of common stock	$ 80,600,000	$ 180,000,000
Common Stock | At The Market Offering
Description Of Organization [Line Items]
Aggregate common stock sold			7,272	170	150
Aggregate common stock value sold			$ 1,000
Common Stock | Underwritten Public Offering
Description Of Organization [Line Items]
Aggregate common stock sold	24,300	21,800
Common Stock | Underwriters' Option To Purchase Additional Shares
Description Of Organization [Line Items]
Aggregate common stock sold	3,400	4,500
Cowen | At The Market Offering
Description Of Organization [Line Items]
Common stock maximum aggregate offering price								$ 119,000,000
Net proceeds from issuance of common stock			$ 28,600,000
Aggregate common stock sold			7,300