Segment reporting (Tables)

9 Months Ended

Sep. 30, 2025

Segment Reporting [Abstract]

Summary of Segment Loss Including Segment Expenses

The table below is a summary of the segment loss, including significant segment expenses (in thousands):

	Three months ended September 30,						Nine months ended September 30,
	2025			2024			2025			2024
	(in thousands)						(in thousands)
Operating expenses:
Support functions	$	12,311		$	17,347		$	39,619		$	56,171
Research, development, and laboratory		10,483			20,454			31,535			68,191
Stock-based compensation		5,475			10,769			19,126			31,241
Technical operations and manufacturing		4,667			9,617			16,615			31,092
Facility costs		5,406			6,083			15,740			18,257
Other(1)		2,049			2,988			6,531			12,339
Research and development related success payments and contingent consideration		3,124			(5,497	)		15,343			4,566
Impairment of long-lived assets		-			-			44,611			-
Total operating expenses		43,515			61,761			189,120			221,857
Loss from operations		(43,515	)		(61,761	)		(189,120	)		(221,857	)
Interest income, net		1,003			2,579			2,572			8,815
Other income (expense), net		360			(742	)		1,207			(4,648	)
Net loss	$	(42,152	)	$	(59,924	)	$	(185,341	)	$	(217,690	)

(1) Other includes licensing costs, consulting fees, insurance, and business taxes for the three and nine months ended September 30, 2025 and 2024.