Organization - Additional Information (Details) - USD ($) shares in Thousands	1 Months Ended	3 Months Ended
	Feb. 29, 2024	Mar. 31, 2025	Mar. 31, 2024	May 08, 2025	Dec. 31, 2024
Description Of Organization [Line Items]
Accumulated deficit		$ 1,654,239,000			$ 1,604,850,000
Cash, cash equivalents and marketable securities		104,700,000
Success payment liabilities		2,200,000
Contingent consideration		59,600,000
Over Allotment Option
Description Of Organization [Line Items]
Number of warrants to purchase common stock	12,700
Net proceeds from issuance of common stock	$ 180,000,000
Common Stock
Description Of Organization [Line Items]
Aggregate common stock sold			21,773
Common Stock | At The Market Offering
Description Of Organization [Line Items]
Aggregate common stock sold			150
Common Stock | Underwritten Public Offering
Description Of Organization [Line Items]
Aggregate common stock sold	21,800
Common Stock | Underwriters' Option To Purchase Additional Shares
Description Of Organization [Line Items]
Aggregate common stock sold	4,500
Pre Funded Warrants [Member] | Over Allotment Option
Description Of Organization [Line Items]
Number of warrants to purchase common stock	12,700
Cowen | At The Market Offering
Description Of Organization [Line Items]
Net proceeds from issuance of common stock		$ 28,500,000
Aggregate common stock sold		4,900
Cowen | At The Market Offering | Subsequent Event
Description Of Organization [Line Items]
Common stock maximum aggregate offering price				$ 119,000,000