Segment reporting (Tables)

3 Months Ended

Mar. 31, 2025

Segment Reporting [Abstract]

Summary of Segment Loss Including Segment Expenses

The table below is a summary of the segment loss, including significant segment expenses (in thousands):

	Three months ended March 31,
	2025			2024
	(in thousands)
Operating expenses:
Facility costs	$	11,232		$	12,105
Research and laboratory		8,846			15,927
Support functions		8,654			13,645
Technical operations and manufacturing		7,436			10,023
Stock-based compensation		7,022			9,093
Clinical development		3,246			7,865
Other(1)		2,237			4,059
Research and development related success payments and contingent consideration		1,957			38,007
Total operating expenses		50,630			110,724
Loss from operations		(50,630	)		(110,724	)
Interest income, net		992			3,034
Other income, net		249			215
Net loss	$	(49,389	)	$	(107,475	)

(1) Other includes licensing costs, consulting fees, insurance and business taxes for the three months ended March 31, 2025 and 2024.