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Organization - Additional Information (Details) - USD ($)
shares in Thousands
1 Months Ended 12 Months Ended
Feb. 29, 2024
Oct. 31, 2023
Feb. 28, 2021
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Aug. 31, 2022
Description Of Organization [Line Items]              
Stock-based compensation expense       $ 35,533,000 $ 38,337,000 $ 22,362,000  
Net proceeds from issuance of common stock       4,626,000 4,312,000 5,346,000  
Proceeds from public offering of common stock, net of offering costs           $ 626,405,000  
Percentage of workforce reduction   29.00%          
Cash-based expenses related to employee severance, benefits and related costs       5,200,000      
Accumulated deficit       1,338,091,000 1,054,836,000    
Cash, cash equivalents and marketable securities       205,200,000      
Success payment liabilities       10,300,000      
Contingent consideration       58,300,000      
At The Market Offering              
Description Of Organization [Line Items]              
Net proceeds from issuance of common stock       $ 27,020,000 $ 601,000    
At The Market Offering | Common Stock              
Description Of Organization [Line Items]              
Aggregate common stock sold       4,586 149    
IPO | Common Stock              
Description Of Organization [Line Items]              
Aggregate common stock sold     27,000     27,025  
Proceeds from public offering of common stock, net of offering costs     $ 626,400,000        
Underwritten Public Offering [Member] | Subsequent Event              
Description Of Organization [Line Items]              
Net proceeds from issuance of common stock $ 179,900,000            
Underwritten Public Offering [Member] | Pre-Funded Warrants | Subsequent Event              
Description Of Organization [Line Items]              
Number of warrants to purchase common stock 12,700            
Underwritten Public Offering [Member] | Common Stock | Subsequent Event              
Description Of Organization [Line Items]              
Aggregate common stock sold 21,800            
Underwritten Public Offering | Subsequent Event              
Description Of Organization [Line Items]              
Net proceeds from issuance of common stock $ 179,900,000            
Underwritten Public Offering | Pre-Funded Warrants | Subsequent Event              
Description Of Organization [Line Items]              
Number of warrants to purchase common stock 12,700            
Underwritten Public Offering | Common Stock              
Description Of Organization [Line Items]              
Aggregate common stock sold     3,500        
Underwritten Public Offering | Common Stock | Subsequent Event              
Description Of Organization [Line Items]              
Aggregate common stock sold 4,500            
Underwriters' Option To Purchase Additional Shares | Common Stock | Subsequent Event              
Description Of Organization [Line Items]              
Aggregate common stock sold 4,500            
Cowen | At The Market Offering              
Description Of Organization [Line Items]              
Common stock maximum aggregate offering price             $ 150,000,000
Net proceeds from issuance of common stock       $ 27,600,000      
Aggregate common stock sold       4,700