X0306 4 2021-02-08 0 0001770121 Sana Biotechnology, Inc. SANA 0001830054 MacDonald James J. C/O SANA BIOTECHNOLOGY, INC. 188 EAST BLAINE STREET, SUITE 400 SEATTLE WA 98102 0 1 0 0 See Remarks Common Stock 2021-02-08 4 C 0 93750 A 428750 D Common Stock 2021-02-08 4 C 0 7812 A 7812 I Held by The James J. MacDonald and Rena Chng Trust dtd 01/15/10 Common Stock 125000 I Held by the NMM Trust Common Stock 125000 I Held by the KOM Trust Series A-1 Convertible Preferred Stock 2021-02-08 4 C 0 93750 0.00 D Common Stock 93750 0 D Series B Convertible Preferred Stock 2021-02-08 4 C 0 7812 0.00 D Common Stock 7812 0 I Held by The James J. MacDonald and Rena Chng Trust dtd 01/15/10 The shares of Issuer's Preferred Stock automatically convert into shares of Issuer's Common Stock, for no additional consideration, on a 1-for-1 basis immediately prior to the consummation of Issuer's initial public offering. The expiration date is not relevant to the conversion of these securities. EVP, General Counsel and Corporate Secretary /s/ James J. MacDonald 2021-02-10