X0306 4 2021-04-19 0 0001357874 PRECISION BIOSCIENCES INC DTIL 0001769828 JANTZ DEREK C/O PRECISION BIOSCIENCES, INC. 302 E. PETTIGREW STREET, SUITE A-100 DURHAM NC 27701 1 1 0 0 Chief Scientific Officer Common Stock 2021-04-19 4 M 0 21514 0.04 A 4026435 D Common Stock 2021-04-19 4 S 0 9676 8.69 D 4016759 D Employee Stock Option (Right to Buy) 0.04 2021-04-19 4 M 0 21514 0.00 D 2021-05-17 Common Stock 21514 64542 D All sales were effected pursuant to a Rule 10b5-1 plan. The transaction was a sell-to-cover exercise, with shares sold to cover the option exercise price and taxes, and the reporting person retaining all remaining shares. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.63 to $8.69. The reporting person undertakes to provide the Company, any security holder of the Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The option is fully vested and exercisable. /s/ Dario Scimeca, Attorney-in-Fact for Derek Jantz 2021-04-21