Exhibit 16.1

December 16, 2024   Securities and Exchange Commission Washington, D.C. 20549 RSM US LLP   801 Nicollet Mall West Tower, Suite 1200 Minneapolis, MN 55402   T +1 612 332 4300 F +1 612 376 9876   www.rsmus.com

Commissioners:

We have read CoreWeave, Inc.’s statements pursuant to Item 304 of Regulation S-K captioned “Change in Independent Accountant” included in its Form S-1 filed on December 16, 2024, and we agree with such

statements concerning our firm.

/s/ RSM US LLP

RSM US LLP