X0306 4 2023-03-10 0 0001768446 Eliem Therapeutics, Inc. ELYM 0001868517 Morisset Valerie C/O ELIEM THERAPEUTICS, INC. 23515 NE NOVELTY HILL RD, STE. B221 #125 REDMOND WA 98053 0 1 0 0 EVP, R&D and CSO Common Stock 2023-03-10 4 M 0 255219 0.002 A 405541 D Common Stock 2023-03-10 4 M 0 61191 0.0002 A 466732 D Stock Option (Right to Buy) 0.002 2023-03-10 4 M 0 255219 0.00 D 2030-02-03 Common Stock 255219 5431 D Stock Option (Right to Buy) 0.0002 2023-03-10 4 M 0 61191 0.00 D 2031-02-25 Common Stock 61191 61190 D The shares subject to this option shall vest at a rate of 12/48ths of the total number of shares on the one-year anniversary of April 1, 2019 (the "April 2019 Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the April 2019 Vesting Commencement Date thereafter (or if there is no corresponding day, on the last day of the month) for so long as the Reporting Person remains an officer, director, employee, consultant and/or advisor of the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the April 2019 Vesting Commencement Date. The shares subject to this option shall vest at a rate of 12/48ths of the total number of shares on the one-year anniversary of February 26, 2021 (the "February 2021 Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the February 2021 Vesting Commencement Date thereafter (or if there is no corresponding day, on the last day of the month) for so long as the Reporting Person remains an officer, director, employee, consultant and/or advisor of the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the February 2021 Vesting Commencement Date. /s/ Brian Woodard, Attorney-in-Fact 2023-03-14