X0206 3 2021-08-09 0 0001768446 Eliem Therapeutics, Inc. ELYM 0001233539 PATTERSON LEONE D C/O ELIEM THERAPEUTICS, INC. 23515 NE NOVELTY HILL RD, STE. B221 #125 REDMOND WA 98053 1 0 0 0 Stock Option (Right to Buy) 1.32 2031-03-05 Common Stock 39198 D Stock Option (Right to Buy) 6.10 2031-04-26 Common Stock 15383 D The shares subject to this option shall vest at a rate of 12/48ths of the total number of shares on the one-year anniversary of March 4, 2021 (the "March 2021 Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the March 2021 Vesting Commencement Date thereafter (or if there is no corresponding day, on the last day of the month) for so long as the Reporting Person remains an officer, director, employee, consultant and/or advisor of the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the March 2021 Vesting Commencement Date. The shares subject to this option shall vest at a rate of 12/48ths of the total number of shares on the one-year anniversary of April 27, 2021 (the "April 2021 Vesting Commencement Date") and 1/48th of the total number of shares each monthly anniversary of the April 2021 Vesting Commencement Date thereafter (or if there is no corresponding day, on the last day of the month) for so long as the Reporting Person remains an officer, director, employee, consultant and/or advisor of the Issuer, such that the total number of shares shall be fully vested on the four-year anniversary of the April 2021 Vesting Commencement Date. /s/ Alan Hambelton, Attorney-in-Fact 2021-08-09