X0407 4 2023-06-16 0001830214 Ginkgo Bioworks Holdings, Inc. DNA 0001767813 Hannan Kathy Hopinkah C/O GINKGO BIOWORKS HOLDINGS, INC. 27 DRYDOCK AVENUE BOSTON MA 02210 1 0 Restricted Stock Units 0 2023-06-16 4 A 0 105263 0 A Class A Common Stock 105263 105263 D Stock Option 1.90 2023-06-16 4 A 0 139860 0 A 2033-06-16 Class A Common Stock 139860 139860 D Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Class A Common Stock. The vesting date of the RSUs and stock options, and in the case of the stock options the date they become exercisable, will be the earlier of (i) June 16, 2024 or (ii) the day immediately prior to the date of the Issuer's next Annual Meeting of Shareholders occurring after the grant date, in either case subject to the Reporting Person continuing in service as a Non-Employee Director of the Issuer through such date. The RSUs have no expiration date. RSUs granted on August 2, 2022 that were initially reported as Class A Common Stock in Table I of a Form 4 dated August 4, 2022 vested in full in shares on June 15, 2023. In accordance with the Issuer's Non-Employee Director Compensation Program, the Black-Scholes value of the option award as of the grant date is $200,000. /s/ Karen Tepichin, Attorney-in-Fact 2023-06-21