X0202 SCHEDULE 13G 0001763945 XXXXXXXX LIVE Common Stock, $0.001 par value per share 03/31/2026 0002100782 Generate Biomedicines, Inc. 370920100 101 South Street, Suite 900 Somerville MA 02143 Rule 13d-1(d) Nally Michael X1 6919051.00 0 6919051.00 0 6919051.00 N 5.2 IN Generate Biomedicines, Inc. 101 South Street, Suite 900, Somerville, MA 02143 This statement is filed on behalf of Michael Nally (the "Reporting Person"). c/o Generate Biomedicines, Inc., 101 South Street, Suite 900, Somerville, MA 02143. The Reporting Person is a citizen of the United States. Y The ownership information below represents beneficial ownership of Common Stock of the Issuer as of March 31, 2026, based upon 128,192,484 shares of Common Stock outstanding as of March 31, 2026, as disclosed by the Issuer in its Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 7, 2026. The Reporting Person may be deemed to be the beneficial owner of 6,919,051 shares of Common Stock, which includes: (i) 572,707 shares of Common Stock held of record by the Reporting Person; (ii) 1,316,654 shares of Common Stock held of record by the MTN 2024 GST Trust; (iii) 999,793 shares of Common Stock held of record by the MTN 2024 GRAT; and (iv) 4,029,897 shares of Common Stock underlying stock options exercisable within 60 days of March 31, 2026 by the Reporting Person. 5.2 6,919,051 0 6,919,051 0 Y Y Y Y Y Y Nally Michael /s/ Michael Nally 05/15/2026