Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Erasca, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation  or Carry Forward Rule

Amount Registered

Proposed Maximum  Offering Price Per Share(3)

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration  Fee

Carry Forward  Form Type

Carry Forward  File Number

Carry Forward Initial Effective  Date

Filing Fee Previously Paid in Connection  with Unsold Securities to be Carried Forward

Fees to Be Paid

Equity

Common Stock, $0.0001 par value per share

Equity

Preferred Stock, $0.0001 par value per share

Debt

Debt Securities

Other

Warrants

Other

Units

Unallocated (Universal) Shelf

457(o)

(1)(2)

(4)

$500,000,000

$92.70 per $1,000,000

$46,350

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

$500,000,000

$46,350

Total Fees Previously Paid

—

Total Fee Offsets

—

Net Fee Due

$46,350

(1) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices, and, in addition, an unspecified number of additional shares of common stock is being registered as may be issued from time to time upon conversion of any debt securities that are convertible into common stock or pursuant to any anti-dilution adjustments with respect to any such convertible debt securities.

(2) Includes rights to acquire common stock or preferred stock of the Company under any shareholder rights plan then in effect, if applicable under the terms of any such plan.

(3) Estimated solely for the purpose of calculating the registration fee. No separate consideration will be received for shares of common stock that are issued upon conversion of debt securities or preferred stock or upon exercise of common stock warrants registered hereunder. The aggregate maximum offering price of all securities issued pursuant to this registration statement will not exceed $500,000,000 (the “Maximum Offering Price”).

(4) Estimated in accordance with Rule 457(o) under the Securities Act of 1933, as amended, solely for the purpose of calculating the registration fee. Amount is based upon the Maximum Offering Price.

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