Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Cash flows from operating activities:
Net loss	$ (98,218,000)	$ (64,980,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	2,131,000	1,849,000
Stock-based compensation expense	14,028,000	13,857,000
In-process research and development expenses	22,500,000
Accretion on marketable securities, net	(4,719,000)	(2,386,000)
Impairment charge on operating lease assets and property and equipment	4,653,000
Impairment charge on investment in equity securities	402,000
Changes in operating assets and liabilities:
Prepaid expenses and other current and long-term assets	(840,000)	1,794,000
Accounts payable	(77,000)	(255,000)
Accrued expenses and other current and long-term liabilities	(2,313,000)	(5,721,000)
Operating lease assets and liabilities, net	19,000	3,533,000
Net cash used in operating activities	(62,434,000)	(52,309,000)
Cash flows from investing activities:
Purchases of marketable securities	(144,333,000)	(199,450,000)
Maturities of marketable securities	90,250,000	126,950,000
In-process research and development	(22,500,000)	(20,000,000)
Purchases of property and equipment	(55,000)	(1,453,000)
Net cash used in investing activities	(76,638,000)	(93,953,000)
Cash flows from financing activities:
Proceeds from issuance of common stock in private placement, net of fees and expenses	43,637,000
Proceeds from issuance of common stock in underwritten offering, net of discounts and offering costs	174,638,000
Proceeds from the exercise of stock options	129,000	305,000
Proceeds from issuance of common stock under the Employee Stock Purchase Plan	395,000	527,000
Net cash provided by financing activities	218,799,000	832,000
Net increase (decrease) in cash, cash equivalents and restricted cash	79,727,000	(145,430,000)
Cash, cash equivalents and restricted cash at beginning of the period	93,483,000	284,625,000
Cash, cash equivalents and restricted cash at end of the period	173,210,000	139,195,000
Supplemental disclosure of noncash investing and financing activities:
Amounts accrued for purchases of property and equipment		33,000
Vesting of early exercised options	310,000	$ 895,000
Amounts accrued for offering costs	245,000
Amounts accrued for deferred offering costs	170,000
Obligation accrued for investment in equity securities	$ 235,000