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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (72,066,000) $ (46,231,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 937,000 318,000
Stock-based compensation expense 9,497,000 2,431,000
In-process research and development expenses 2,000,000 9,168,000
Amortization on marketable securities, net 5,000 46,000
Change in fair value of preferred stock purchase right liability   (1,615,000)
Changes in operating assets and liabilities:    
Prepaid expenses and other current and long-term assets (4,571,000) (3,498,000)
Accounts payable 14,000 580,000
Accrued expenses and other current liabilities (646,000) 4,984,000
Operating lease assets and liabilities, net 11,883,000 (82,000)
Net cash used in operating activities (52,947,000) (33,899,000)
Cash flows from investing activities:    
Purchases of marketable securities (22,290,000) (31,911,000)
Maturities of marketable securities 27,200,000 42,910,000
In-process research and development (2,000,000) (6,000,000)
Payment made for investment in equity securities (2,000,000)  
Purchases of property and equipment (11,895,000) (701,000)
Net cash (used in) provided by investing activities (10,985,000) 4,298,000
Cash flows from financing activities:    
Proceeds from the issuance of convertible preferred stock, net of issuance costs   119,393,000
Proceeds from the exercise of stock options, net of repurchases 835,000 1,324,000
Proceeds from issuance of common stock under the Employee Stock Purchase Plan 617,000  
Net cash provided by financing activities 1,452,000 120,717,000
Net (decrease) increase in cash, cash equivalents and restricted cash (62,480,000) 91,116,000
Cash, cash equivalents and restricted cash at beginning of the period 360,895,000 65,688,000
Cash, cash equivalents and restricted cash at end of the period 298,415,000 156,804,000
Supplemental disclosure of noncash investing and financing activities:    
Issuance of common stock in connection with asset acquisition   1,680,000
Issuance of common stock in connection with license agreement   5,488,000
Amounts accrued for purchases of property and equipment 1,178,000 101,000
Vesting of early exercised options 717,000 348,000
Amounts accrued for deferred offering costs   $ 1,930,000
Supplemental Disclosure of Noncash Operating Activities [Abstract]    
Operating lease assets obtained in exchange for lease obligation 916,000  
Tenant improvement allowance included in operating lease liabilities 6,483,000  
Reduction in operating lease assets due to lease amendment $ 3,361,000