Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (Unaudited) - USD ($) $ in Thousands	Total	Convertible Preferred Stock	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Convertible preferred stock, beginning balance, shares at Dec. 31, 2020		69,584,682
Convertible preferred stock, beginning balance, value at Dec. 31, 2020		$ 221,405
Beginning balance, shares at Dec. 31, 2020			25,189,673
Beginning balance at Dec. 31, 2020	$ (113,984)		$ 3	$ 1,413	$ 2	$ (115,402)
Issuance of Series B-1 and B-2 convertible preferred stock for cash, shares		15,931,772
Issuance of Series B-1 and B-2 convertible preferred stock for cash		$ 119,393
Issuance of common stock in connection with asset acquisition, shares			500,000
Issuance of common stock in connection with asset acquisition	1,680			1,680
Exercise of stock options, shares			439,610
Exercise of stock options	94			94
Vesting of early exercised stock options	174			174
Stock-based compensation expense	795			795
Net loss	(18,017)					(18,017)
Unrealized loss on marketable securities, net	(1)				(1)
Convertible preferred stock, ending balance, shares at Mar. 31, 2021		85,516,454
Convertible preferred stock,ending balance, value at Mar. 31, 2021		$ 340,798
Ending balance, shares at Mar. 31, 2021			26,129,283
Ending balance at Mar. 31, 2021	(129,259)		$ 3	4,156	1	(133,419)
Convertible preferred stock, beginning balance, shares at Dec. 31, 2020		69,584,682
Convertible preferred stock, beginning balance, value at Dec. 31, 2020		$ 221,405
Beginning balance, shares at Dec. 31, 2020			25,189,673
Beginning balance at Dec. 31, 2020	(113,984)		$ 3	1,413	2	(115,402)
Net loss	(46,231)
Convertible preferred stock, ending balance, shares at Jun. 30, 2021		85,516,454
Convertible preferred stock,ending balance, value at Jun. 30, 2021		$ 340,798
Ending balance, shares at Jun. 30, 2021			27,300,123
Ending balance at Jun. 30, 2021	(149,997)		$ 3	11,634	(1)	(161,633)
Convertible preferred stock, beginning balance, shares at Mar. 31, 2021		85,516,454
Convertible preferred stock, beginning balance, value at Mar. 31, 2021		$ 340,798
Beginning balance, shares at Mar. 31, 2021			26,129,283
Beginning balance at Mar. 31, 2021	(129,259)		$ 3	4,156	1	(133,419)
Issuance of common stock in connection with license agreement, shares			944,945
Issuance of common stock in connection with license agreement	5,488			5,488
Exercise of stock options, shares			225,895
Exercise of stock options	180			180
Vesting of early exercised stock options	174			174
Stock-based compensation expense	1,636			1,636
Net loss	(28,214)					(28,214)
Unrealized loss on marketable securities, net	(2)				(2)
Convertible preferred stock, ending balance, shares at Jun. 30, 2021		85,516,454
Convertible preferred stock,ending balance, value at Jun. 30, 2021		$ 340,798
Ending balance, shares at Jun. 30, 2021			27,300,123
Ending balance at Jun. 30, 2021	$ (149,997)		$ 3	11,634	(1)	(161,633)
Convertible preferred stock, beginning balance, shares at Dec. 31, 2021		0
Beginning balance, shares at Dec. 31, 2021	121,382,547		121,382,547
Beginning balance at Dec. 31, 2021	$ 456,528		$ 12	694,844	(162)	(238,166)
Exercise of stock options, shares			357,244
Exercise of stock options	460			460
Vesting of early exercised stock options	479			479
Repurchases of early exercised stock options and restricted stock, Shares			(6,945)
Stock-based compensation expense	4,442			4,442
Net loss	(36,458)					(36,458)
Unrealized loss on marketable securities, net	(789)				(789)
Ending balance, shares at Mar. 31, 2022			121,732,846
Ending balance at Mar. 31, 2022	$ 424,662		$ 12	700,225	(951)	(274,624)
Convertible preferred stock, beginning balance, shares at Dec. 31, 2021		0
Beginning balance, shares at Dec. 31, 2021	121,382,547		121,382,547
Beginning balance at Dec. 31, 2021	$ 456,528		$ 12	694,844	(162)	(238,166)
Net loss	$ (72,066)
Convertible preferred stock, ending balance, shares at Jun. 30, 2022		0
Ending balance, shares at Jun. 30, 2022	122,063,473		122,063,473
Ending balance at Jun. 30, 2022	$ 395,067		$ 12	706,510	(1,223)	(310,232)
Beginning balance, shares at Mar. 31, 2022			121,732,846
Beginning balance at Mar. 31, 2022	424,662		$ 12	700,225	(951)	(274,624)
Exercise of stock options, shares			179,985
Exercise of stock options	375			375
Issuance of common stock under the Employee Stock Purchase Plan, Shares			150,642
Issuance of common stock under the Employee Stock Purchase Plan	617			617
Vesting of early exercised stock options	238			238
Stock-based compensation expense	5,055			5,055
Net loss	(35,608)					(35,608)
Unrealized loss on marketable securities, net	$ (272)				(272)
Convertible preferred stock, ending balance, shares at Jun. 30, 2022		0
Ending balance, shares at Jun. 30, 2022	122,063,473		122,063,473
Ending balance at Jun. 30, 2022	$ 395,067		$ 12	$ 706,510	$ (1,223)	$ (310,232)