Common stock, Class A common stock and convertible preferred stock (Details) $ / shares in Units, $ in Thousands				1 Months Ended		2 Months Ended	9 Months Ended
	Sep. 30, 2022 USD ($) Vote $ / shares shares	Mar. 04, 2022 USD ($) $ / shares shares	Feb. 15, 2022 USD ($) $ / shares shares	Aug. 31, 2022 shares	Jul. 31, 2022 shares	Aug. 31, 2022 shares	Sep. 30, 2022 USD ($) Vote $ / shares shares	Mar. 31, 2022 $ / shares	Dec. 31, 2021 shares
Preferred stock, shares authorized	10,000,000						10,000,000		10,000,000
Net proceeds from public offering | $		$ 70,200
Proceeds from issuance of common stock, net of issuance costs | $							$ 45,691
Register for resale of common stock			4 months
Common stock
Common stock, shares authorized	200,000,000						200,000,000		100,000,000
Common stock, issued (in shares)	52,317,138						52,317,138		27,383,483
Common stock, outstanding (in shares)	52,317,138						52,317,138		27,383,483
Issuance of common stock		21,700,000
Share Price | $ / shares		$ 2.00
Number of votes | Vote	1						1
Shares issued upon conversion of redeemable convertible preferred stock (in shares)						1,420,215
Class A common stock
Common stock, shares authorized	3,900,000						3,900,000		3,900,000
Common stock, issued (in shares)	2,399,517						2,399,517		3,819,732
Common stock, outstanding (in shares)	2,399,517						2,399,517		3,819,732
Number of common stock issued upon conversion of each share							1
Number of shares elected to convert				650,481	769,734	1,420,215
Series A Convertible Preferred Stock
Preferred stock shares Designated	2,978						2,978		2,978
Preferred stock, shares issued	1,697						1,697
Preferred stock, shares outstanding	1,697						1,697		1,697
Series A -1 Convertible Preferred Stock
Preferred stock shares Designated	15,800						15,800		0
Preferred stock, shares issued	15,800						15,800
Preferred stock, shares outstanding	15,800						15,800		0
Issuance of common stock		15,800
Share Price | $ / shares		$ 2,000.00
Series A and Series A-1 convertible preferred stock
Number of common stock issued upon conversion of each share							1,000
Threshold percentage for conversion	9.99%						9.99%
Liquidation preference per share | $ / shares	$ 0.001						$ 0.001
Stock Purchase Agreement
Net proceeds from public offering | $			$ 35,000
Issuance of common stock			1,666,666
Proceeds from issuance of common stock, net of issuance costs | $			$ 5,000
Share Price | $ / shares			$ 3.00
Outstanding amount | $	$ 30,000		$ 30,000
Percentage of premium			30.00%
Stock Purchase Agreement | Gilead | Gilead Collaboration and License Agreement
Ownership percentage			19.90%
Stock Purchase Agreement | Common stock
Share Price | $ / shares								$ 3.00