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Receivable research incentive (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Receivable research incentive          
Receivable research incentive $ 17,300   $ 17,300   $ 14,271
Income related to the incentive program recorded as grant income $ 2,000 $ 2,300 $ 5,400 $ 6,600