Property, plant and equipment, net (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Property and equipment
Property and equipment, gross	$ 23,170	$ 22,718
Less: Accumulated depreciation	(6,654)	(6,366)
Property and equipment, net	16,516	16,352
Land
Property and equipment
Property and equipment, gross	1,791	2,072
Leasehold improvements
Property and equipment
Property and equipment, gross	2,894	3,348
Construction in progress
Property and equipment
Property and equipment, gross	9,603	7,746
Laboratory equipment
Property and equipment
Property and equipment, gross	6,476	7,025
Furniture and fixtures
Property and equipment
Property and equipment, gross	568	651
Computer equipment and software
Property and equipment
Property and equipment, gross	$ 1,838	$ 1,876

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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