Summary of significant accounting policies - Property and equipment (Details)	9 Months Ended
	Sep. 30, 2022
Laboratory equipment | Minimum
Property and equipment
Estimated useful life (in years)	2 years
Laboratory equipment | Maximum
Property and equipment
Estimated useful life (in years)	10 years
Furniture and fixtures | Minimum
Property and equipment
Estimated useful life (in years)	2 years
Furniture and fixtures | Maximum
Property and equipment
Estimated useful life (in years)	10 years
Computer equipment and software | Minimum
Property and equipment
Estimated useful life (in years)	2 years
Computer equipment and software | Maximum
Property and equipment
Estimated useful life (in years)	4 years