X0306 4 2022-01-03 0 0001401040 DiaMedica Therapeutics Inc. DMAC 0001759855 Parsons James T. TWO CARLSON PARKWAY SUITE 260 MINNEAPOLIS MN 55447 1 0 0 0 Voting Common Shares, no par value per share 2022-01-03 4 A 0 16773 3.58 A 38509 D These shares are issuable upon settlement of deferred stock units granted under the DiaMedica Therapeutics Inc. 2019 Omnibus Incentive Plan in lieu of cash retainer fees in the aggregate amount of $60,000. Amount reflects the cancellation of 211 shares underlying deferred share units granted in lieu of Board committee retainers due to a change in Board committee memberships. Includes 3,850 voting common shares issuable upon settlement of deferred share units granted under the DiaMedica Therapeutics Inc. Deferred Share Unit Plan and 32,409 shares issuable upon settlement of deferred stock units granted under the DiaMedica Therapeutics Inc. 2019 Omnibus Incentive Plan. /s/ Amy Culbert, attorney-in-fact 2022-01-03