X0508 4 2025-01-02 0 0001401040 DiaMedica Therapeutics Inc. DMAC 0001759822 Giuffre Randall Michael 301 CARLSON PARKWAY, SUITE 210 MINNEAPOLIS MN 554305 1 0 0 0 0 Voting Common Shares, no par value per share 2025-01-02 4 A 0 10861 5.34 A 375412 D Voting Common Shares, no par value per share 25573 I See footnote Voting Common Shares, no par value per share 21070 I By Spouse These shares are issuable upon settlement of deferred stock units granted under the DiaMedica Therapeutics Inc. Amended and Restated 2019 Omnibus Incentive Plan in lieu of cash retainer fees in the aggregate amount of $58,000. The deferred stock units will vest in four nearly equal installments on each of March 31, 2025, June 30, 2025, September 30, 2025 and December 31, 2025. Includes 4,146 voting common shares issuable upon settlement of deferred share units granted under the DiaMedica Therapeutics Inc. Deferred Share Unit Plan, 95,016 shares issuable upon settlement of deferred stock units granted under the DiaMedica Therapeutics Inc. 2019 Omnibus Incentive Plan, as amended from time to time, 164,890 voting common shares held by Michael Giuffre and his wife jointly and 111,360 voting common shares held by Michael Giuffre individually. These voting common shares are held by 424822 Albert Ltd, of which Michael Giuffre has sole voting and dispositive power. /s/ Amy E. Culbert, attorney-in-fact 2025-01-03