144 0001974200 XXXXXXXX LIVE 0001759425 MIRUM PHARMACEUTICALS, INC. 001-38981 989 East Hillsdale Boulevard Suite 300 Foster City CA 94404 (650) 667-4085 JOLANDA MARIE HOWE Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

2415 107342.89 49014190 03/18/2025 NASDAQ Common 03/15/2025 Performance Shares ISSUER N 2415 03/15/2025 Not Applicable N JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 03/17/2025 2900 128221.62 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 03/17/2025 598 26526.80 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 03/17/2025 708 31406.31 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 03/17/2025 500 22179.60 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 03/17/2025 52900 2346427.11 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 02/03/2025 1064 51308.77 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 01/24/2025 902 43227.82 JOLANDA MARIE HOWE

989 East Hillsdale Boulevard Suite 300 Foster City CA 94404

Common 01/07/2025 750 32111.45 03/18/2025 12/16/2024 /s/ Jolanda Howe