Organization and Description of Business - Additional Information (Detail) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021 USD ($) Segment $ / shares shares	Dec. 31, 2020 USD ($) shares
Date of incorporation	May 02, 2018
Number of operating segment | Segment	1
Accumulated deficit	$ 257,159	$ 173,171
Cash, cash equivalents and investments	261,500
Unrestricted cash, cash equivalents and investments	161,500
Gain on Sale of Priority Review Voucher	$ 108,000	$ 0
Common Stock Shares Issued | shares	30,705,060	30,032,600
S V B Leerink Limited Liability Company [Member]
Sale Of Stock Number Of Shares Issued In Transaction | shares	992,389
Sale Of Stock Consideration Received On Transaction	$ 17,400
Weighted-average exercise price, Granted | $ / shares	$ 18.04