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Income Taxes - Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]    
U.S. federal provision at statutory rate 21.00% 21.00%
State income taxes, net of federal benefit 0.70% 2.90%
Tax credits 0.60% 1.90%
Fair value of financial instruments (15.60%) (6.80%)
Stock-based compensation expense (0.40%) (0.60%)
Uncertain tax benefits (0.30%) (0.90%)
Change in valuation allowance (6.00%) (17.50%)
Effective tax rate 0.00% (0.00%)