Exhibit 107

Calculation of Filing Fee Tables

Form S-1

(Form Type)

SHUTTLE PHARMACEUTICALS HOLDINGS, INC.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

	Security Type	Security Class Title	Fee Calculation Rule		Amount Registered(1)		Proposed Maximum Offering Price Per Unit		Maximum Aggregate Offering Price(1)		Fee Rate		Amount of Registration Fee(2)
Fees to be paid	Equity	Common stock, par value $0.00001 per share		457(o)		-		-	$	6,500,000	$	153.10 per $1,000,000	$	995.15
	Other	Pre-funded warrants to purchase common stock(3)		457(g)		-		-		-		-		-
	Equity	Common stock, par value $$0.00001 per share, underlying pre-funded warrants(2)(4)		457(o)		-		-		-		-		-
Carry Forward Securities	-	-		-		-		-		-		-		-
	Total Offering Amounts								$	6,500,000	$	153.10 per $1,000,000	$	995.15
	Total Fee Offsets
	Fees Previously Paid
	Net Fee Due												$	995.15

(1)	Estimated solely for the purpose of calculating the amount of the registration fee in accordance with Rule 457(o) under the Securities Act of 1933, as amended (the “Securities Act”).
(2)	Pursuant to Rule 416 under the Securities Act, this registration statement shall also cover any additional shares of the registrant’s securities that become issuable by reason of any share splits, share dividends or similar transactions.
(3)	No separate registration fee is payable pursuant to Rule 457(g) under the Securities Act. In accordance with Rule 457(i) under the Securities Act, no separate registration fee is required with respect to the pre-funded warrants registered hereby.
(4)	The registrant may issue pre-funded warrants to purchase common stock in the offering. The purchase price of each pre-funded warrant will be equal to the price per share at which shares are being sold to the public in this offering, minus $0.001 per share, which constitutes the pre-funded portion of the exercise price of the pre-funded warrants. The remaining unpaid exercise price of the pre-funded warrants will equal $0.001 per share (subject to adjustment as provided for therein). The proposed maximum aggregate offering price of the shares of common stock will be reduced on a dollar-for-dollar basis based on the offering price of any pre-funded warrants issued in the offering and vice versa. Accordingly, the proposed maximum aggregate offering price of the shares of common stock and pre-funded warrants is $6,500,000.