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Intangible assets (Details) - EUR (€)
€ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jan. 01, 2021
Intangible assets        
Balance, at the beginning of the year € 9,194 € 12,407    
Balance, at the end of the year 7,400 9,194 € 12,407  
Intangible assets 7,400 9,194 12,407 € 12,407
Biomarkers and databases        
Intangible assets        
Impairment expense 158 1,067 4,700  
Internally generated /acquired | Biomarkers        
Intangible assets        
Balance, at the beginning of the year 1,545 3,174    
Balance, at the end of the year 906 1,545 3,174  
Intangible assets 906 1,545 3,174  
Internally generated /acquired | Database        
Intangible assets        
Balance, at the beginning of the year 6,396 6,506    
Balance, at the end of the year 6,066 6,396 6,506  
Intangible assets 6,066 6,396 6,506  
Internally generated /acquired | Centometabolome        
Intangible assets        
Balance, at the beginning of the year 2,540 1,099    
Balance, at the end of the year 2,181 2,540 1,099  
Intangible assets € 2,181 2,540 1,099  
Remaining useful life 6 years      
Purchased | Rights, licenses, software        
Intangible assets        
Balance, at the beginning of the year € 1,253 2,727    
Balance, at the end of the year 428 1,253 2,727  
Intangible assets 428 1,253 2,727  
Cost        
Intangible assets        
Balance, at the beginning of the year 30,827 28,040 21,534  
Additions 1,727 2,787 6,657  
Deconsolidation     (151)  
Balance, at the end of the year 32,554 30,827 28,040  
Intangible assets 32,554 30,827 28,040  
Cost | Internally generated /acquired | Biomarkers        
Intangible assets        
Balance, at the beginning of the year 14,374 13,922 12,022  
Additions 162 749 1,900  
Reclassification   (297)    
Balance, at the end of the year 14,536 14,374 13,922  
Intangible assets 14,536 14,374 13,922  
Cost | Internally generated /acquired | Database        
Intangible assets        
Balance, at the beginning of the year 11,168 9,219 6,502  
Additions 1,515 1,652 2,717  
Reclassification   297    
Balance, at the end of the year 12,683 11,168 9,219  
Intangible assets 12,683 11,168 9,219  
Cost | Purchased | Rights, licenses, software        
Intangible assets        
Balance, at the beginning of the year 5,285 4,899 3,010  
Additions 50 386 2,040  
Deconsolidation     (151)  
Balance, at the end of the year 5,335 5,285 4,899  
Intangible assets 5,335 5,285 4,899  
Accumulated depreciation, amortization and impairment        
Intangible assets        
Balance, at the beginning of the year (21,633) (15,633) (7,389)  
Amortization and impairment 3,521 6,000 8,368  
Deconsolidation     (124)  
Balance, at the end of the year (25,154) (21,633) (15,633)  
Intangible assets (25,154) (21,633) (15,633)  
Accumulated depreciation, amortization and impairment | Internally generated /acquired | Biomarkers        
Intangible assets        
Balance, at the beginning of the year (12,829) (10,748) (3,831)  
Amortization and impairment 801 2,149 6,917  
Reclassification   (68)    
Balance, at the end of the year (13,630) (12,829) (10,748)  
Intangible assets (13,630) (12,829) (10,748)  
Accumulated depreciation, amortization and impairment | Internally generated /acquired | Database        
Intangible assets        
Balance, at the beginning of the year (4,772) (2,713) (1,770)  
Amortization and impairment 1,845 1,991 943  
Reclassification   68    
Balance, at the end of the year (6,617) (4,772) (2,713)  
Intangible assets (6,617) (4,772) (2,713)  
Accumulated depreciation, amortization and impairment | Purchased | Rights, licenses, software        
Intangible assets        
Balance, at the beginning of the year (4,032) (2,172) (1,788)  
Amortization and impairment 875 1,860 508  
Deconsolidation     (124)  
Balance, at the end of the year (4,907) (4,032) (2,172)  
Intangible assets € (4,907) € (4,032) € (2,172)