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Intangible assets (Details) - EUR (€)
€ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Intangible assets    
Balance, at the beginning of the year € 12,407  
Balance, at the end of the year 9,194 € 12,407
Biomarkers and databases    
Intangible assets    
Impairment expense 1,100  
Internally generated /acquired | Biomarkers    
Intangible assets    
Balance, at the beginning of the year 3,174  
Balance, at the end of the year 1,545 3,174
Internally generated /acquired | Database    
Intangible assets    
Balance, at the beginning of the year 6,506  
Reclass 229  
Balance, at the end of the year 6,396 6,506
Purchased | Rights, licenses, software    
Intangible assets    
Balance, at the beginning of the year 2,727  
Balance, at the end of the year 1,253 2,727
Cost    
Intangible assets    
Balance, at the beginning of the year 28,040 21,534
Additions 2,787 6,657
Deconsolidation   (151)
Balance, at the end of the year 30,827 28,040
Cost | Internally generated /acquired | Biomarkers    
Intangible assets    
Balance, at the beginning of the year 13,922 12,022
Additions 749 1,900
Reclass 297  
Balance, at the end of the year 14,374 13,922
Cost | Internally generated /acquired | Database    
Intangible assets    
Balance, at the beginning of the year 9,219 6,502
Additions 1,652 2,717
Reclass (297)  
Balance, at the end of the year 11,168 9,219
Cost | Purchased | Rights, licenses, software    
Intangible assets    
Balance, at the beginning of the year 4,899 3,010
Additions 386 2,040
Deconsolidation   (151)
Balance, at the end of the year 5,285 4,899
Accumulated depreciation, amortization and impairment    
Intangible assets    
Balance, at the beginning of the year (15,633) (7,389)
Deconsolidation   (124)
Amortization and impairment 6,000 8,368
Balance, at the end of the year (21,633) (15,633)
Accumulated depreciation, amortization and impairment | Internally generated /acquired | Biomarkers    
Intangible assets    
Balance, at the beginning of the year (10,748) (3,831)
Deconsolidation 68  
Amortization and impairment 2,149 6,917
Balance, at the end of the year (12,829) (10,748)
Accumulated depreciation, amortization and impairment | Internally generated /acquired | Database    
Intangible assets    
Balance, at the beginning of the year (2,713) (1,770)
Deconsolidation (68)  
Amortization and impairment 1,991 943
Balance, at the end of the year (4,772) (2,713)
Accumulated depreciation, amortization and impairment | Purchased | Rights, licenses, software    
Intangible assets    
Balance, at the beginning of the year (2,172) (1,788)
Deconsolidation   (124)
Amortization and impairment 1,860 508
Balance, at the end of the year € (4,032) € (2,172)