144 0001757072 XXXXXXXX LIVE 0002044725 Evommune, Inc. 001-42938 1891 Page Mill Road Palo Alto CA 94304 925-247-4481 KYLE CARVER Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

25675 599254.50 36018372 05/28/2026 NYSE Common 05/28/2026 Exercise of Stock Options Issuer N 22500 05/28/2026 Cash Common 04/26/2023 Pre-IPO Purchase of Common Shares Issuer N 3175 04/26/2023 Cash Y The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale. 05/28/2026 02/26/2026 /s/ Kyle Carver