X0306 4 2021-11-09 1 0001557142 Kadmon Holdings, Inc. KDMN 0001757072 Carver Kyle C/O KADMON HOLDINGS, INC. 450 E. 29TH STREET NEW YORK NY 10016 0 1 0 0 SVP, CAO, Controller Common Stock 2021-11-09 4 D 0 15420 9.50 D 0 D Stock Option (right to buy) 4.66 2021-11-09 4 D 0 45000 4.84 D 2026-12-15 Common Stock, par value $0.001 45000 0 D Stock Option (right to buy) 3.64 2021-11-09 4 D 0 55000 5.86 D 2027-12-08 Common Stock, par value $0.001 55000 0 D Stock Option (right to buy) 2.47 2021-11-09 4 D 0 50000 7.03 D 2028-12-14 Common Stock, par value $0.001 50000 0 D Stock Option (right to buy) 4.34 2021-11-09 4 D 0 100000 5.16 D 2030-01-27 Common Stock, par value $0.001 100000 0 D Stock Option (right to buy) 3.96 2021-11-09 4 D 0 175000 5.54 D 2031-01-08 Common Stock, par value $0.001 175000 0 D Disposed pursuant to the acquisition by Sanofi of the entire issued share capital of Issuer on November 9, 2021 by means of a plan of merger (the "Merger"). In connection with the Merger, all unvested stock options ("Options") were accelerated to full vesting and cancelled in exchange for a payment equal to $9.50 with respect to each share of Common Stock subject to such Option. Represents the payment per share of Common Stock received in exchange for the cancellation of each Option. /s/ Gregory S. Moss, Attorney-in-Fact 2021-11-09