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Operating Expense (Tables)
12 Months Ended
Dec. 31, 2021
Operating Expense [Abstract]  
Summary of Operating Expenses and Other Operating Income
Operating expenses and other operating income (expenses)Year endedOf which :
2019/12/31RawContractedEmployeeOtherDepreciation,Gain /
materialsresearch andexpensesexpensesamortization(loss) on
anddevelopment(maintenance,anddisposal of
consumablesactivitiesfees, travel,impairmentproperty,
usedconducted bytaxes…)chargesplant and
(in € thousands)third partiesequipment
Research and development expenses(66,170)(2,017)(41,509)(11,740)(6,188)(4,716)— 
General and administrative expenses(17,265)(177)(59)(7,598)(8,972)(458)— 
Marketing and market access expenses(13,708)(8)— (1,645)(11,979)(76)— 
Reorganization and restructuring expenses— — — — — — — 
Other operating income (expenses)(1,649)— — — (1,668)— 19 
TOTAL(98,793)(2,202)(41,568)(20,984)(28,807)(5,251)19 
(*) : including reversals
Operating expenses and other operating income (expenses)Year endedOf which :
2020/12/31RawContractedEmployeeOtherDepreciation,Gain /
materialsresearch andexpensesexpensesamortization(loss) on
anddevelopment(maintenance,anddisposal of
consumablesactivitiesfees, travel,impairmentproperty,
usedconducted bytaxes…)chargesplant and
(in € thousands)third partiesequipment
Research and development expenses(59,097)(1,876)(39,216)(11,554)(5,465)(985)— 
General and administrative expenses(14,270)(202)(92)(6,936)(6,545)(495)— 
Marketing and market access expenses(11,216)(7)(2)(1,298)(9,818)(90)— 
Reorganization and restructuring expenses(5,308)— — (2,141)(3,175)— 
Other operating income (expenses)(764)— — — (684)— (80)
TOTAL(90,655)(2,085)(39,310)(19,779)(24,655)(4,746)(80)
(*) : including reversals
Operating expenses and other operating income (expenses)Year endedOf which :
2021/12/31RawContractedEmployeeOtherDepreciation,Gain /
materialsresearch andexpensesexpensesamortization(loss) on
anddevelopment(maintenance,anddisposal of
consumablesactivitiesfees, travel,impairmentproperty,
usedconducted bytaxes…)chargesplant and
(in € thousands)third partiesequipment
Research and development expenses(35,166)(1,305)(18,808)(8,192)(4,593)(2,247)(19)
General and administrative expenses(16,153)(161)(85)(7,379)(8,003)(541)15 
Marketing and market access expenses(1,539)(1)(1)(783)(741)(13)— 
Reorganization and restructuring expenses(142)(5)— — (2,343)2,206 — 
Other operating income (expenses)(763)— — — (338)(429)
TOTAL(53,763)(1,472)(18,895)(16,354)(16,019)(591)(433)
(*) : including reversals
Summary of Employee Expenses and Number of Employees
Employee expenses and number of employees were as follows:
Employee expensesYear ended
(in € thousands)2019/12/312020/12/312021/12/31
Wages and salaries(14,018)(13,570)(10,328)
Social security costs(5,171)(5,047)(4,775)
Changes in pension provision(138)74 (154)
Employee profit-sharing— — (628)
Share-based compensation(1,657)(1,236)(470)
TOTAL(20,984)(19,779)(16,354)
Number of employees at year-end - detailYear ended
2019/12/312020/12/312021/12/31
Average number of employees175193122
Number of employees
Research and development1086655
Services related to research and development191618
Administration and management604347
Marketing and commercial752
TOTAL194 130 122 
Number of employees
Senior staff14410597
Staff452321
Others (apprentices)524
TOTAL194130122
Number of employees
Male785245
Female1167877
TOTAL194130122