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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities:    
Net loss $ (44,215) $ (28,748)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 1,817 1,577
Stock-based compensation expense 6,878 2,414
Non-cash interest and end of term accretion expense 540 511
Non-cash lease expense 829  
Net amortization of premiums on marketable securities 1,356 634
Unrealized foreign currency transaction (gains) losses 928 (1,065)
Changes in operating assets and liabilities:    
Accounts receivable 840 (218)
Inventory (4,894) (1,740)
Prepaid expenses and other current assets (3,151) (769)
Accounts payable 5,090 (5,802)
Accrued expenses and other current liabilities 4,875 1,948
Deferred revenue 7 60
Operating lease liabilities 236  
Deferred rent   933
Net cash used in operating activities (28,864) (30,265)
Cash flows from investing activities:    
Purchases of property and equipment (3,519) (455)
Purchases of marketable securities (72,024) (121,793)
Proceeds from sales and maturities of marketable securities 104,810 80,650
Net cash provided by (used) in investing activities 29,267 (41,598)
Cash flows from financing activities:    
Proceeds from issuance of common stock in public offering, net of underwriting discounts and commissions   75,670
Payments of public offering and other financing costs   (705)
Proceeds from issuance of common stock upon exercise of stock options 974 227
Proceeds from issuance of common stock in connection with employee stock purchase plan 419 357
Proceeds from Paycheck Protection Program loan   2,249
Repayment of Paycheck Protection Program loan   (2,249)
Net cash provided by financing activities 1,393 75,549
Effect of exchange rate changes on cash, cash equivalents and restricted cash (797) 803
Net increase in cash, cash equivalents and restricted cash 999 4,489
Cash, cash equivalents and restricted cash, beginning of period 25,081 20,592
Cash, cash equivalents and restricted cash, end of period 26,080 25,081
Supplemental disclosure of cash flow information:    
Cash paid for interest 3,334 3,475
Supplemental disclosure of non-cash investing and financing activities:    
Transfers of inventory to property and equipment 1,823 1,191
Purchases of property and equipment included in accounts payable and accrued expenses 1,200  
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 25,580 24,581
Restricted cash 500 500
Cash, cash equivalents and restricted cash, end of period $ 26,080 $ 25,081