Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Accounting Policies [Abstract]
Net loss	$ 44,215	$ 28,748
Accumulated deficit	442,446	$ 398,231
Cash equivalents and marketable securities	$ 92,500