X0306 4 2022-08-11 0 0001756262 TransMedics Group, Inc. TMDX 0001430466 Hassanein Waleed H C/O TRANSMEDICS GROUP, INC. 200 MINUTEMAN ROAD ANDOVER MA 01810 1 1 0 0 President & CEO Common Stock 2022-08-11 4 S 0 12929 46.74 D 493285 D Common Stock 2022-08-12 4 S 0 7000 48.00 D 486285 D Represents a sale of shares of common stock to generate cash for the payment of taxes, including estimated taxes, due as a result of the vesting or settlement of certain equity-based awards or the exercise of stock options as permitted by the lock-up agreement, dated August 3, 2022, among the Reporting Person, J.P. Morgan Securities LLC, Morgan Stanley & Co. LLC and Cowen and Company, LLC as the representatives of the underwriters named therein. The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $46.39 to $47.26, inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. By: /s/ Stephen Gordon, Attorney-in-Fact 2022-08-15